stationary phase
IRI: https://spec.industrialontologies.org/ontology/construct/StationaryPhase
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/
SubClass Of: bfo:material entity
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › stationary phase
Definition
material entity with a stationary phase role
Semi-Formal Definition:
every instance of ‘stationary phase’ is defined as exactly an instance of ‘material entity’ that ‘has role’ some ‘stationary phase role’
Explanatory Notes
Common terms such as “chromatographic bed” or “sorbent” may refer to its various physical forms. To avoid ambiguity, expressions like “liquid stationary phase” or “solid stationary phase” are preferred when specifying its physical state.
Examples
- Silica gel as stationary phase in normal-phase chromatography; C18 bonded silica as stationary phase in reverse-phase chromatography; agarose bead gel as stationary phase in size-exclusion chromatography; ion-exchange resin as stationary phase in ion-exchange chromatography; protein A immobilized on resin as stationary phase in affinity chromatography; polymeric resin as stationary phase in hydrophobic interaction chromatography.
Counter-Examples
- an unpacked chromatography column; chromatography medium when it is offered for sale by its manufacturer
Formal Axioms
First-Order Logic Definition
StationaryPhase(x) ↔ MaterialEntity(x) ∧ ∃r(StationaryPhaseRole(r) ∧ hasRole(x, r))
Description Logic
constr:StationaryPhase ≡ bfo:material_entity ⊓ ∃ constr:hasRole .constr:StationaryPhaseRole
constr:StationaryPhase ⊑ bfo:material_entity
EquivalentTo: bfo:material_entity and constr:hasRole some constr:StationaryPhaseRole
SubClassOf: bfo:material_entity