cell line lineage
IRI: https://spec.industrialontologies.org/ontology/construct/CellLineLineage
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: bfo:history
Class Hierarchy
owl:Thing › bfo:entity › bfo:occurrent › bfo:process › bfo:history › cell line lineage
Definition
history of the development of a cell line
Semi-Formal Definition:
every instance of ‘cell line lineage’ is defined as exactly an instance of ‘history’ that ‘is history of’ some ‘cell line’
Explanatory Notes
The cell line lineage may include the original cell type from a tissue and organism that derives the cell line cell. It may also include the cell line passage and cell culturing information.
Examples
- HEK293 history: derived from human embryonic kidney cells transfected with adenovirus 5 DNA; selected for stable growth in culture;
Synonyms
- cell line history
Adapted From
- CLO:0000171
Formal Axioms
First-Order Logic Definition
CellLineLineage(x) ↔ History(x) ∧ ∃y(CellLine(y) ∧ historyOf(x, y))
Description Logic
constr:CellLineLineage ≡ bfo:history ⊓ ∃ bfo:history_of .constr:CellLine
constr:CellLineLineage ⊑ bfo:history
EquivalentTo: bfo:history and bfo:history_of some constr:CellLine
SubClassOf: bfo:history