filtration process

IRI: https://spec.industrialontologies.org/ontology/construct/FiltrationProcess

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaManufacturingExecution/

SubClass Of: planned process

Class Hierarchy

owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › filtration process

Direct subclasses:

• depth filtration process
• direct flow filtration
• membrane filtration process
• tangential flow filtration

Definition

planned process in which suspended solids or dissolved components are separated from a fluid by passing it through a filter

Explanatory Notes

1) Passing can be conducted by using gravity or by using pressure. 2) According to the direction of the fluid feed in relation to the filter medium there are two broad types of filtrations. In conventional (a.k.a normal, direct, perpendicular) l filtration, the fluid flows perpendicular to the medium which results in a cake of solids depositing on the filter medium. In tangential flow filtration the fluid flows parallel to the medium to minimize buildup of solids on the medium. Given that flow direction is the key differentiating characteristic, tangential flow filtration and normal flow filtration are modeled as defined subclasses of filtration. 3) Filtration is a separation technique predominantly based on particle size, where components are retained or passed through a porous medium depending on their dimensions relative to the pore size. However, in some cases, additional characteristics such as particle shape and electrostatic charge can significantly influence retention behavior and selectivity of the filter used in the process.

Examples

• depth filtration; TFF filtration; direct flow filtration; membrane filtration

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

Insufficient constructs are present to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

FiltrationProcess(x) → PlannedProcess(x) ∧ ∃y (Filter(y) ∧ hasParticipantAtSomeTime(x, y))

Semi-Formal Natural Language Axioms

if x is a ‘filtration process’ then x is a ‘planned process’ and ‘has participant at some time’ some ‘filter’

Description Logic

constr:FiltrationProcess ⊑ constr:PlannedProcess

constr:FiltrationProcess ⊑ ∃ bfo:has_participant .constr:Filter

SubClassOf: constr:PlannedProcess

SubClassOf: bfo:has_participant some constr:Filter